Last name Sebastiani (Sebastiani 
) , all around the world, is a common cognomen. The last name Sebastiani is habitual in Italy, where it is quite a common surname, Luxembourg, where it is quite a rare surname, and Tanzania. Measured by absolute frequency, the name is most common in Italy, Tanzania, and Brazil. Much less frequently, Sebastiani is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Sebastiani | Peru, Tanzania, Argentina, Italy, Brazil |
Sebastiano, Sébastiani, and Себастиани
| sebastiano sebastiani Italian sculptor, IT (b. 1550) |
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| johann sebastiani German composer, DE (b. 1622) |
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| johann christoph sebastiani German architect, DE (b. 1640) |
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| johannes philipp sebastiani DE (b. 1708) |
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| franz joseph sebastiani FR (b. 1722) |
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| antonio sebastiani Italian painter (1743-1818) (b. 1743) |
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| francisco sebastiani (b. 1764) |
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| francesco antonio sebastiani physician and naturalist (1782–1821) (b. 1782) |
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| constanze sebastiani (b. 1796) |
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| ferdinando sebastiani IT (b. 1803) |
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| giovanni sebastiani composer (b. 1818) |
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| ferdinando sebastiani clarinetist, teacher (1823-1860), IT (b. 1823) |
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| francesco sebastiani Italian politician (1827-1878), IT (b. 1827) |
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| carlo sebastiani composer (1858-1924) (b. 1858) |
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sergio sebastiani Catholic cardinal, IT (b. 1931) |
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