Family name Opazo (Opazo 
) , all over the world, is a common cognomen. The surname Opazo is habitual in Latin America and the Caribbean, particularly Chile, where it is quite a common surname, Argentina, where it is quite a rare surname, and Paraguay. Much less frequently, Opazo is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Opazo | Paraguay, Spain, Argentina, Brazil, Chile |
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pedro opazo Chilean politician (1876-1957), CL (b. 1876) |
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| eduardo opazo letelier Chilean politician (1865-1925), CL (b. 1865) |
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ramón pérez opazo Chilean politician, CL (b. 1933) |
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rodolfo opazo Chilean painter, CL (b. 1935) |
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| carlos opazo aparicio Chilean footballer, CL (b. 1901) |
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| rudolfo opazo Chilean artist (b. 1935) |
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héctor zambrano opazo |
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óscar opazo Chilean association football player, CL (b. 1990) |
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diego opazo Chilean footballer, CL (b. 1991) |
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| roberto opazo castro Chilean psychotherapist, CL (b. 1943) |
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| mario opazo Colombian artist, CL (b. 1969) |
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| francisca opazo Chilean actor, CL (b. 1975) |
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| ismael opazo researcher |
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| maria pilar opazo Ph.D. Columbia University 2014 |
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| luis opazo researcher |
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