Surname Mcguffie (Mcguffie 
) , throughout the world, is quite a rare cognomen. The surname Mcguffie is habitual in the United Kingdom, where it is a rare surname, Australia, and Estonia. In absolute terms, this name is the most popular in the United States, the United Kingdom, and Australia.
| VARIANT | COUNTRY |
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| Mcguffie | United Kingdom, Australia, United States, Canada, New Zealand |
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louis mcguffie recipient of the Victoria Cross, GB (b. 1893) |
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| walter mcguffie British wrestler, GB (b. 1916) |
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| bill mcguffie British musician, GB (b. 1927) |
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ryan mcguffie Scottish footballer (born 1980), GB (b. 1980) |
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sam mcguffie player of American football, US (b. 1989) |
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| k. mcguffie (b. 1960) |
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| andrew w. mcguffie Peerage person ID=575246 |
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| jane fairie wilson mcguffie (died 1989) |
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| jocelyn mary mcguffie Peerage person ID=575247 |
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| thomas chalmers mcguffie (died 1932) |
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| craig mcguffie association football player (b. 1997) |
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| will mcguffie association football player, GB |
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