Cognomen Manzione (Manzione 
) , in all the world, is quite a rare surname. The family name Manzione is habitual in Argentina, where it is quite a rare surname, Uruguay, and Italy. Measured by absolute frequency, it is the most numerous in Italy, Argentina, and the United States. Much less frequently, Manzione is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Manzione | Argentina, Italy, Brazil, United States, Uruguay |
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homero nicolás manzione Argentine tango lyricist (1907-1951), AR (b. 1907) |
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roberto manzione Italian politician and lawyer, IT (b. 1953) |
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| fulvio manzione person identified in the Museu da Pessoa collection, BR (b. 1936) |
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| domenico manzione Italian magistrate and politician, IT (b. 1955) |
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| nicoletta manzione Italian journalist, IT (b. 1966) |
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| carlo manzione Italian hellenist (1969-), IT (b. 1969) |
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| lauren c manzione researcher (ORCID 0000-0002-6420-0170) |
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| chuck manzione college basketball player (1948–1950) Saint Mary's (CA) |
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| adolfo manzione |
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| nicola manzione IT (b. 1983) |
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