Last name Spyrou (Spyrou 
, Σπύρου ) , throughout the world, is quite a common surname. The family name Spyrou is habitual in Cyprus, where it is a common surname, Marshall Islands, where it is quite a common surname, and Greece. Measured by absolute frequency, it is the most numerous in Greece, Cyprus, and the United Kingdom.
| VARIANT | COUNTRY |
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| Spyrou | United Kingdom, Australia, Romania, Greece, Cyprus |
| Σπύρου | Greece |
| panagiotis spyrou Greek weightlifter (b. 1947) |
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| george spyrou Scottish businessman (1949-2010) (b. 1949) |
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| panayiotis spyrou Cypriot footballer, CY (b. 1976) |
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| christos spyrou Greek weightlifter, GR (b. 1976) |
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| maria spyrou researcher (ORCID 0000-0003-2320-6573) |
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| evaggelos spyrou researcher (ORCID 0000-0003-2067-9949) |
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| maria a spyrou researcher |
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| konstantinos spyrou researcher |
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| c. spyrou researcher, ORCID id # 0000-0002-3074-3230, GR |
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| leonidas spyrou researcher |
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| artemis spyrou Experimental nuclear astrophysicist |
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| christiana spyrou Ph.D. University of Cambridge 2009 |
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| george m spyrou researcher (ORCID 0000-0002-2470-3363) |
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| spyros i. spyrou economist (Athens University of Economics and Business (AUEB)) |
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| james spyrou researcher (ORCID 0000-0002-9302-4962) |
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