Cognomen Santillo (Santillo 
) , globally, is quite a rare family name. The cognomen Santillo is habitual in Italy, where it is quite a rare surname, Malta, and Argentina, where it is a rare surname. Not in comparison with a country's population, it is commonest in Italy, the United States, and Brazil. Much less frequently, Santillo is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Santillo | Brazil, Italy, Argentina, United States, Mexico |
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emilio santillo italian police officer, IT (b. 1909) |
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will santillo Canadian photographer, US (b. 1953) |
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| gennaro santillo Italian association football player (1908-1943), IT (b. 1908) |
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| juvenal santillo Brazilian association football player, BR (b. 1910) |
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| frank santillo American film editor (1912-1978), US (b. 1912) |
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| umberto santillo Italian association football player, IT (b. 1912) |
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agostino santillo Italian politician, IT (b. 1974) |
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| henrique santillo Brazilian politician, BR (b. 1937) |
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| adhemar santillo Brazilian politician (1939-2021), BR (b. 1939) |
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| walter santillo Italian television presenter, IT (b. 1959) |
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| roberto santillo Italian comics artist, IT (b. 1962) |
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| marco santillo Italian economic historian (1965-), IT (b. 1965) |
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| alessandra santillo researcher (ORCID 0000-0002-8313-6821) |
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| silvia santillo researcher |
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| bruna tereso santillo researcher (ORCID 0000-0003-2851-1657) |
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