Surname Santacroce (Santacroce 
) , across the world, is quite a common cognomen. The surname Santacroce is habitual in Aruba, where it is quite a common surname, Italy, where it is quite a rare surname, and Argentina, where it is a rare surname. Not in comparison with a country's population, it is the most numerous in Italy, the United States, and Argentina. Very seldom, Santacroce is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Santacroce | Germany, Italy, United States, Argentina, France |
| andrea santacroce (b. 1402) |
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girolamo da santacroce 16th-century Italian painter, IT (b. 1480) |
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| francesco di simone da santacroce Italian painter, ca. 1440-1508, IT (b. 1440) |
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prospero santacroce Italian Roman Catholic bishop and cardinal, IT (b. 1514) |
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| francesco rizzo da santacroce Italian painter (1490-1545), IT (b. 1490) |
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| francesco rizzo di bernado da santacroce (b. 1485) |
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| girolamo santacroce 16th-century Italian sculptor, IT (b. 1502) |
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| francesco di girolamo da santacroce Italian artist (1516-1584) (b. 1516) |
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| ottavio santacroce Roman Catholic bishop and nuncio (b. 1542) |
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marcello santacroce Italian cardinal (1619-1674), IT (b. 1619) |
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| pietro paolo da santacroce Italian painter, documented 1584-1620 (b. 1584) |
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| antonio santacroce Italian cardinal (1598-1641), IT (b. 1598) |
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andrea santacroce Italian cardinal (1655-1712), IT (b. 1655) |
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| antonio santacroce (b. 1599) |
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| rocco santacroce Italian politician (1896-1981), IT (b. 1896) |
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