Cognomen Mihalache (Mihalache 
) , worldwide, is a common last name. The last name Mihalache is characteristic of Romania, where it is a common surname, Andorra, where it is quite a common surname, and Moldova, where it is quite a rare surname. Not in comparison with a country's population, it most frequently occurs in Romania, Italy, and Moldova. Very seldom, Mihalache is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Mihalache | Moldova, Romania, Afghanistan, Italy, Spain |
| mihalache ghica Romanian archaeologist (1792-1854) (b. 1792) |
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ion mihalache Romanian politician, RO (b. 1882) |
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dan mihalache Romanian politician, RO (b. 1971) |
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marcel mihalache Romanian rugby union footballer and coach, RO (b. 1971) |
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ina mihalache Canadian actress, CA (b. 1985) |
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| vasile mihalache Romanian politician, RO (b. 1939) |
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mihaela mihalache Romanian painter, RO (b. 1992) |
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| andrei mihalache Romanian accordionist, RO (b. 1944) |
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| dumitru mihalache Romanian physicist, RO (b. 1948) |
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| dumitru mihalache Romanian lawyer and sportsman, RO (b. 1951) |
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| cornel mihalache Romanian journalist, RO (b. 1963) |
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| lucia mihalache Olympic skeet shooter, RO (b. 1967) |
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| george mihalache Romanian musician, RO (b. 1971) |
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| marius mihalache Romani musician, RO (b. 1974) |
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| dragoș mihalache Romanian footballer, RO (b. 1975) |
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