Family name Luppino (Luppino 
) , worldwide, is quite a rare last name. The surname Luppino is characteristic of Italy, where it is quite a rare surname, Australia, and Argentina, where it is a rare surname. Measured by absolute frequency, it is commonest in Italy, the United States, and Argentina. Much less frequently, Luppino is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Luppino | Australia, Italy, United States, Argentina, France |
| thomas william luppino (b. 1790) |
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carmine luppino Italian sportsperson and gymnast, IT (b. 1948) |
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| art luppino American-football player (1930-) (b. 1930) |
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| vicente luppino Argentinian racecar driver, AR (b. 1953) |
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| susan luppino (b. 1945) |
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| giuseppe luppino Italian librarian (1957-), IT (b. 1957) |
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| giuseppe luppino Italian physiologist (1957-), IT (b. 1957) |
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| leonardo luppino footballer, AR (b. 1975) |
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| jennifer m luppino researcher (ORCID 0000-0002-2078-7619) |
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| marc anders luppino Ph.D. University of California, Los Angeles 2010 |
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| gerard a. luppino researcher |
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