Surname Knuckles (Knuckles 
) , globally, is quite a rare cognomen. The cognomen Knuckles is characteristic of Liberia, where it is quite a rare surname, the United States, where it is a rare surname, and Ghana.
| VARIANT | COUNTRY |
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| Knuckles | United Kingdom, United States, Liberia, Ghana, Canada |
| william knuckles American football coach, US (b. 1928) |
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mickie knuckles American professional wrestler, US (b. 1984) |
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| philip knuckles researcher ORCID ID = 0000-0001-5254-8244 |
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| bettie nelson knuckles Ph.D. The University of North Carolina at Chapel Hill 1983 |
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| richard knuckles American bobsledder, US |
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| craig knuckles Ph.D. Louisiana State University 1995 |
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| travis knuckles |
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| charles butler knuckles |
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