Cognomen Santone (Santone 
) , around the globe, is quite a rare last name. The last name Santone is habitual in Italy, where it is quite a rare surname, Argentina, and Australia, where it is a rare surname. Measured by absolute frequency, it most frequently occurs in Italy, the United States, and Argentina. Very seldom, Santone is the forename as well as the last name.
| joe santone Italian American football player (1893–1963), IT (b. 1893) |
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| bryan santone researcher (ORCID 0000-0003-0359-5719) |
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| antonella santone |
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