Last name Santillana (Santillana 
) , in the entire world, is a common surname. The last name Santillana is characteristic of Latin America and the Caribbean, particularly El Salvador, where it is quite a common surname, Belize, and Peru, where it is quite a rare surname. Measured by absolute frequency, it most frequently occurs in Philippines, Mexico, and Peru. Very seldom, Santillana is the forename as well as the last name.
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| Santillana | Spain, Mexico, Philippines, Peru, El Salvador |
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gervasio santillana Peruvian sailor and military personnel (1853-1907), PE (b. 1853) |
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| david santillana Italian lawyer and orientalist (1855-1931), TN (b. 1855) |
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| ludovico diaz de santillana (Italian, 1931–1989) (b. 1931) |
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| ludovico de santillana IT (b. 1931) |
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| luís miguel santillana Spanish basketball player, ES (b. 1951) |
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| alessandro diaz de santillana glass artist; sculptor, FR (b. 1959) |
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| laura diaz de santillana IT (b. 1955) |
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| jorge santillana Mexican association football player, MX (b. 1969) |
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| alessandro de santillana IT (b. 1959) |
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| eterio ortega santillana (b. 1962) |
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| mauricio santillana researcher |
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| irene a espinosa de santillana researcher |
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| francisco de santillana Roman Catholic bishop |
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| antonio ruiz de santillana Spanish writer, ES |
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| sergio santillana researcher |
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