Cognomen O'Donohue (O'Donohue 
) , all around the world, is quite a rare surname. The last name O'Donohue is habitual in Ireland, where it is quite a rare surname, Australia, and New Zealand, where it is a rare surname. Measured by absolute frequency, it most frequently occurs in Australia, Ireland, and the United States.
| VARIANT | COUNTRY |
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| O'Donohue | United Kingdom, Australia, Ireland, United States, Canada |
Donoghue, and O'Donoghue
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michael o'donohue American architect, US (b. 1835) |
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| peter o'donohue Australian rules footballer and coach, AU (b. 1923) |
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| phil o'donohue Australian rules footballer, AU (b. 1926) |
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daniel j. o'donohue American Marine Corps general |
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| daniel anthony o'donohue American diplomat (b. 1931) |
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| maura o'donohue Catholic doctor and religious, IE (b. 1933) |
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| tony o'donohue Toronto City Councillor, CA (b. 1933) |
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| thomas o'donohue American printmaker, US (b. 1942) |
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| john o'donohue Irish writer, priest and philosopher, IE (b. 1956) |
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| william t o'donohue American psychologist, US (b. 1957) |
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| barry o'donohue (b. 1947) |
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| edward o'donohue Australian politician, AU (b. 1974) |
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| michael j o'donohue researcher |
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| john f. o'donohue American actor, US |
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| daniel j. o'donohue U.S. Marine major general |
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