Cognomen O'Bryant (O'Bryant 
) , across the world, is a rare family name. The surname O'Bryant is characteristic of the United States, where it is a rare surname, the United Kingdom, where it is a very rare surname, and Canada. In absolute terms, it is commonest in the United States, the United Kingdom, and Germany.
| VARIANT | COUNTRY |
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| O'Bryant | Germany, Canada, United Kingdom, India, United States |
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hugh o'bryant American politician, US (b. 1813) |
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| jimmy o'bryant American jazz clarinetist, US (b. 1896) |
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| john d. o'bryant African American educator, US (b. 1931) |
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patrick o'bryant American basketball player, US (b. 1986) |
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| darrin o'bryant college basketball player (1988–1989) Eastern Kentucky |
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| kevin o'bryant Ph.D. University of Illinois at Urbana-Champaign 2002 |
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| eathan o'bryant college basketball player (1994–1995) Nevada |
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| danny o'bryant American tennis player |
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| orin o'bryant college basketball player (2012–2012) Hampton |
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| greg o'bryant US (b. 1977) |
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| sid o'bryant researcher |
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