Surname Mtsweni (Mtsweni 
) , around the world, is a common family name. The last name Mtsweni is habitual in Sub-Saharan Africa, particularly South Africa, where it is quite a common surname.
| VARIANT | COUNTRY |
|---|---|
| Mtsweni | Australia, Germany, South Africa, United Kingdom, United States |
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refilwe mtsweni South African politician, 5th Premier of Mpumalanga Province, ZA (b. 1973) |
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| thulani mtsweni South African actor |
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| simphiwe mtsweni football player (b. 1994) |
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