Cognomen Mdluli (Mdluli 
) , throughout the world, is a common surname. The cognomen Mdluli is habitual in Sub-Saharan Africa, particularly Eswatini, where it is a widespread surname, South Africa, where it is quite a common surname, and Botswana, where it is quite a rare surname. In absolute terms, it most frequently occurs in Sub-Saharan Africa, particularly South Africa, Eswatini, and Zimbabwe. Very seldom, Mdluli is the forename as well as the last name.
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| Mdluli | Eswatini, Zimbabwe, Botswana, Kenya, South Africa |
| labotsibeni mdluli Swazi royal regent (b. 1859) |
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| richard mdluli South African police officer, ZA (b. 1958) |
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| sizwe sydney mdluli Swazi athletics competitor, SZ (b. 1969) |
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| john mdluli Swazi footballer, SZ (b. 1972) |
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| anthony mdluli Swazi football manager, SZ |
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| phumlane selby mdluli researcher (ORCID 0000-0002-1554-783X) |
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| thembi mdluli researcher |
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| thembani mdluli Toronto-based writer, filmmaker, and media artist, CA |
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| mlungisi mdluli Association footballer, ZA (b. 1980) |
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| mlondi mdluli Swazi association football player (1984-2006), SZ (b. 1984) |
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| siyabonga mdluli association football player (b. 1986) |
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