Surname Macafee (Macafee 
) , globally, is a rare family name. The family name Macafee is habitual in Australia, where it is a rare surname, New Zealand, and the United Kingdom. Not in comparison with a country's population, it is commonest in the United States, the United Kingdom, and Australia.
| VARIANT | COUNTRY |
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| Macafee | Australia, New Zealand, United Kingdom, United States, Canada |
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ken macafee American football player (1929-2007), US (b. 1929) |
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| charles horner greer macafee British clinician, GB (b. 1898) |
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| ken macafee American football player (born 1956), US (b. 1956) |
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| lauren macafee researcher |
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| william macafee Northern Irish election candidate |
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| john leeper anketell macafee Peerage person ID=303682 |
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| elizabeth ann macafee Peerage person ID=303683 |
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