Cognomen Hupe (Hupe 
) , globally, is quite a rare last name. The last name Hupe is characteristic of Germany, where it is quite a rare surname, Cyprus, and Canada, where it is a rare surname. Measured by absolute frequency, this name is the most popular in Germany, the United States, and Canada. Much less frequently, Hupe is the forename as well as the last name.
| klaus hupe German surgeon and university teacher, DE (b. 1928) |
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christopher hupe German politician, DE (b. 1987) |
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| lucie hupe DE (b. 1930) |
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| erich hupe DE (b. 1932) |
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| dirk hupe German association football player, DE (b. 1957) |
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| dirk hupe German artist, graphic designer, photographer and designer, DE (b. 1960) |
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| burkhard hupe DE (b. 1950) |
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| peter l. hupe (b. 1951) |
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| joachim hupe (b. 1965) |
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| mike hupe researcher |
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| andre marc hupe particle physicist |
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| tess hupe researcher |
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| lex hupe Dutch politician, NL |
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| meghan hupe researcher |
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| lukas hupe researcher (ORCID 0000-0002-0977-5457) |
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