Last name Esperón (Esperón 
) , across the world, is a rare cognomen. The surname Esperón is habitual in Uruguay, where it is quite a rare surname, Cuba, and Spain, where it is a rare surname.
| VARIANT | COUNTRY |
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| Esperón | Uruguay, Mexico, Spain, Argentina, Cuba |
| ángel maría hernández esperón CU (b. 1900) |
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| iván esperón Argentine footballer and manager (1912-2000), AR (b. 1912) |
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soledad esperón Argentinian tennis player, AR (b. 1985) |
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| alejandro duprat esperón Mexican hornist, MX (b. 1963) |
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| natalia esperón Mexican actress, MX (b. 1974) |
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| fernando esperón researcher |
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| jorge lizcano esperón politician |
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| juan pablo e. esperón |
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| ezequiel esperón Argentinian association football player (1996-2019), AR (b. 1996) |
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Ana, José, Jorge, Jesus, Julia, Tania, Nubia, Oscar, Marcos, María, Manuel, Samuel, Silvia, Susana, Sergio, Alicia, Andrea, Analia, Carlos, Ramiro, Daniel, Jaimel, Jaime, Laura, Diana, Raúl, Sara, Alba, Agni, Chio, Bren, Rosa, Lara, Luci, Luis, Jose, Javier, Juan, Hugo, Maria, Mario, Marco, Mateo, Mauro, Aline, Azúl, Pablo, Pilar, Elia, and Jimena