Last name D'Ercole (D'Ercole 
) , across the world, is quite a rare surname. The family name D'Ercole is habitual in Italy, where it is quite a rare surname, Argentina, where it is a rare surname, and Switzerland. Not in comparison with a country's population, it is commonest in Italy, Argentina, and the United States. Much less frequently, D'Ercole is the forename as well as the last name.
| VARIANT | COUNTRY |
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| D'Ercole | Italy, France, Canada, United States, Argentina |
| pasquale d'ercole Italian philosopher and teacher, IT (b. 1831) |
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lorenzo d'ercole Italian basketball player, IT (b. 1988) |
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| vincenzo d'ercole Italian archaeologist (1952-), IT (b. 1952) |
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| maria cecilia d'ercole (b. 1960) |
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| christine d'ercole athlete and fitness instructor (b. 1971) |
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| giuliana d'ercole Ph.D. Università Degli Studi di Modena e Reggio Emilia 2008 |
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| annibale d'ercole researcher |
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| simonetta d'ercole researcher |
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| claude d'ercole |
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| robert d'ercole |
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| saverio d'ercole IT |
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