Cognomen Spuy (Spuy 
) , across the world, is a rare last name. The family name Spuy is habitual in South Africa, where it is a rare surname, New Zealand, and Netherlands. Measured by absolute frequency, it most frequently occurs in South Africa, Netherlands, and the United Kingdom.
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| Spuy | Australia, Netherlands, New Zealand, United Kingdom, South Africa |
| petrus van der spuy South African minister, ZA (b. 1722) |
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| kenneth van der spuy South African air force officer (b. 1892) |
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| johannes petrus van der spuy South African politician (1912-2003), ZA (b. 1912) |
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nibs van der spuy South African guitarist, ZA (b. 1966) |
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| martin van der spuy (b. 1951) |
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| roelie van der spuy (b. 1956) |
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| gian d van der spuy researcher |
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| wendy j van der spuy researcher ORCID ID = 0000-0003-1892-073X |
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| ina van der spuy researcher |
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| anri van der spuy South African business executive |
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| simóne van der spuy South African art director and illustrator |
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| loek spuy NL |
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| michael van der spuy South African rugby union footballer, ZA (b. 1991) |
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