Cognomen Spena (Spena 
) , in the entire world, is quite a rare last name. The family name Spena is habitual in Italy, where it is quite a rare surname, Argentina, where it is a rare surname, and Switzerland. Not in comparison with a country's population, it most frequently occurs in Italy, Argentina, and the United States. Much less frequently, Spena is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Spena | Argentina, United States, Brazil, India, Italy |
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giovanni russo spena Italian politician, IT (b. 1945) |
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| lita spena Argentine composer (b. 1904) |
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| maria spena Italian politician, IT (b. 1962) |
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| angelo spena researcher ORCID ID = 0000-0001-5992-648X |
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| maria terese spena Italian carcinologist, IT |
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| pasquale russo spena researcher ORCID ID = 0000-0003-0307-2344 |
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| concetta russo spena researcher |
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| silvia spena researcher |
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| angela spena researcher |
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| rossella spena researcher |
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| vincenzo andrea spena researcher |
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| gianluca spena researcher |
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| angelo spena |
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| angelo spena |
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| fabio spena Swiss cyclist, CH (b. 1999) |
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