Family name Semple (Semple 
, סמפל 
) , throughout the world, is quite a common cognomen. The family name Semple is habitual in Marshall Islands, where it is a common surname, Antigua and Barbuda, where it is quite a common surname, and Suriname. In absolute terms, the name is most common in the United States, the United Kingdom, and Canada.
| william semple Scottish exile who lived in Spain, GB (b. 1546) |
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| john semple seventeenth century minister in Ulster and Scotland (b. 1602) |
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| samuel semple Church of Scotland minister and historian (1666-1742) (b. 1666) |
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| george semple Irish architect (b. 1700) |
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| mary semple (b. 1693) |
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james semple British adventurer (b. 1759) |
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robert semple Canadian businessman, CA (b. 1777) |
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james semple American politician from Illinois (1798-1866), US (b. 1798) |
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| robert semple American writer, US (b. 1766) |
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| robert b. semple American Baptist minister (b. 1769) |
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letitia tyler semple daughter of the American president, US (b. 1821) |
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andrew semple Canadian politician, CA (b. 1837) |
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eugene semple American politician (1840-1908), US (b. 1840) |
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| john semple Irish architect (b. 1801) |
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etta semple American politician (1854-1914), US (b. 1854) |
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