Family name Orpen (Orpen 
) , globally, is a rare surname. The last name Orpen is characteristic of Lesotho, where it is quite a rare surname, Ireland, and Australia, where it is a rare surname. Measured by absolute frequency, it is the most numerous in the United Kingdom, South Africa, and the United States. Much less frequently, Orpen is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Orpen | United Kingdom, South Africa, Lesotho, Australia, United States |
| richard orpen (1652-1716) (b. 1652) |
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| richard orpen (1727-1770) (b. 1727) |
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| richard orpen (born 1736) (b. 1736) |
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charles orpen Irish doctor, IE (b. 1791) |
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| edward orpen major of the Kerry Volunteers (b. 1741) |
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| francis orpen (1747-1805) (b. 1747) |
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joseph orpen South African politician (1828-1923), ZA (b. 1828) |
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| abraham edward orpen (1779-1836) (b. 1779) |
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rebecca dulcibella orpen English artist, GB (b. 1830) |
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| richard john theodor orpen (b. 1788) |
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abe orpen Canadian businessman, CA (b. 1854) |
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grace orpen wife of Sir William Orpen, GB (b. 1878) |
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william orpen Irish artist (1878–1931), IE (b. 1878) |
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| arthur orpen (1830-1926) (b. 1830) |
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| edward chatterton orpen (1831-1902) (b. 1831) |
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