Family name O'Bryan (O'Bryan 
) , in the world, is quite a rare surname. The cognomen O'Bryan is habitual in Australia, where it is quite a rare surname, the United States, where it is a rare surname, and Ireland. In absolute terms, it is commonest in the United States, Australia, and the United Kingdom. Very seldom, O'Bryan is the forename as well as the last name.
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| O'Bryan | United Kingdom, Australia, Mauritius, Canada, United States |
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william o'bryan English Methodist preacher and founder of the Bible Christian movement., GB (b. 1778) |
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| norman o'bryan (1894-1968) judge, AU (b. 1894) |
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| arthur o'bryan Australian footballer (1923-1990), AU (b. 1923) |
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| ronald clark o'bryan American murderer, US (b. 1944) |
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| james o'bryan, jr. American politician, US (b. 1956) |
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| sean o'bryan actor, US (b. 1963) |
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| moira o'bryan researcher (b. 1966) |
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| timothy o'bryan murder victim (b. 1966) |
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| edward o'bryan researcher (ORCID 0000-0001-9959-4598) |
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| john p o'bryan researcher |
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| sean r o'bryan researcher |
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| laurence o'bryan (b. 1970) |
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| jane o'bryan researcher |
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| laurence o'bryan IE (b. 1970) |
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| derek o'bryan college basketball player (2009–2009) East Carolina |
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