Family name Letsinger (Letsinger 
) , in the entire world, is a rare cognomen. The family name Letsinger is characteristic of the United States, where it is a rare surname, the United Kingdom, where it is a very rare surname, and Canada. Measured by absolute frequency, it is the most numerous in the United States, the United Kingdom, and Germany.
| VARIANT | COUNTRY |
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| Letsinger | Germany, Canada, Brazil, United Kingdom, United States |
| jim letsinger American football player (1911-2002), US (b. 1911) |
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| robert l. letsinger American chemist (1921-2014), US (b. 1921) |
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| william c. letsinger, ii Ph.D. Virginia Polytechnic Institute and State University 1995 |
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| sarah letsinger researcher (ORCID 0000-0001-6211-8918) |
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