Cognomen Keithley (Keithley 
) , in the world, is quite a rare surname. The last name Keithley is habitual in the United States, where it is a rare surname, New Zealand, and Canada. In absolute terms, it is commonest in the United States, the United Kingdom, and Canada. Much less frequently, Keithley is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Keithley | Canada, Philippines, United Kingdom, United States, Saint Kitts and Nevis |
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joe keithley musician and politician, CA (b. 1956) |
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| joseph f. keithley American entrepreneur (1915-1999), US (b. 1915) |
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| george keithley (b. 1935) |
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| june keithley broadcaster, PH (b. 1947) |
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| gary keithley American football player, US (b. 1951) |
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| elizabeth m keithley researcher (ORCID 0000-0001-7710-5052) |
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| richard b keithley researcher |
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| sarah e keithley researcher (ORCID 0000-0002-3510-8690) |
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