Surname De Luca (De Luca 
, Deluca ) , globally, is a common family name. The family name De Luca is habitual in Italy, where it is quite a common surname, Argentina, and Canada, where it is quite a rare surname. Not in comparison with a country's population, the name is most common in Italy, the United States, and Argentina.
| VARIANT | COUNTRY |
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| Deluca, De Luca | Italy, France, Canada, United States, Argentina |
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giovanni battista de luca Catholic cardinal, IT (b. 1614) |
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| severo de luca (b. 1650) |
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| benedetto de luca IT (b. 1684) |
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antonio maria de luca Italian presbyter and patriot, IT (b. 1764) |
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| bonifacio de luca Italian poet, IT (b. 1727) |
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ferdinando de luca Italian geographer and politician, IT (b. 1785) |
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placido de luca Italian politician (1803-1861), IT (b. 1803) |
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antonio saverio de luca cardinal, IT (b. 1805) |
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| salvatore de luca Roman Catholic archbishop (b. 1769) |
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| giuseppe de luca IT (b. 1760) |
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| francesco de luca Italian politician, jurist (1800–1854), IT (b. 1800) |
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| gregorio de luca roman-catholic archbishop (1801-1878) (b. 1801) |
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| domenico de luca author (19th century) (b. 1801) |
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| nicola de luca Italian politician, IT (b. 1811) |
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| francesco de luca Italian politician, lawyer (1811–1875), IT (b. 1811) |
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