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Last name Antoniou (Antoniou , אנטוניו , Антониу ) , throughout the world, is a common cognomen. The last name Antoniou is characteristic of Cyprus, where it is a prevalent surname, Greece, where it is a common surname, and Luxembourg, where it is quite a rare surname. Measured by absolute frequency, it is the most numerous in Greece, Cyprus, and the United Kingdom. Much less frequently, Antoniou is the forename as well as the last name.