Globally, Afrânio (Afranio 
, Afrânio 
) is quite a common male first name. The first name Afrânio is characteristic of Brazil, where it is quite a rare male name, Peru, where it is a rare masculine name, and Portugal. Measured by absolute frequency, it is the most numerous in Latin America and the Caribbean, particularly Brazil, Peru, and Colombia. Very seldom, Afrânio is the last name as well as the forename.
| VARIANT | COUNTRY |
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| Afranio | Brazil, Peru, Colombia, Ecuador, Venezuela |
| Afrânio | Brazil, Cabo Verde, United States, Angola |
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afrânio de melo franco Brazilian diplomat and politician, BR (b. 1870) |
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afrânio da costa sport shooter, BR (b. 1892) |
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afrânio do amaral Brazilian herpetologist, BR (b. 1894) |
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afrânio rodrigues da cunha Brazilian politician, BR (b. 1907) |
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afrânio salgado lages Brazilian politician, BR (b. 1911) |
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afrânio coutinho Brazilian professor, literary critic, librarian and essayist., BR (b. 1911) |
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afrânio pessoa Brazilian painter (1930-2017), BR (b. 1930) |
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| afrânio de oliveira Brazilian journalist (1919-1986), BR (b. 1919) |
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| afrânio messias alves nunes Brazilian politician (1924-2011), BR (b. 1924) |
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| afrânio fernandes botanist (b. 1927) |
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| afrânio melo Brazilian musician, BR (b. 1948) |
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| afrânio riul Brazilian association football player (1949-1996), BR (b. 1949) |
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| afrânio boppré Brazilian politician, BR (b. 1960) |
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| afrânio tadeu boppré politician from Brazil, BR (b. 1960) |
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| afrânio marques Brazilian journalist, BR (b. 1961) |
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Sá, Machado, Moreira, Miranda, Almeida, Araújo, Barbosa, Pereira, Ribeiro, Galdino, Júnior, Medeiros, Silveira, Carvalho, Teixeira, Nogueira, Ferreira, Oliveira, Rodrigues, Magalhães, Cavalcante, Gonçalves, Marques, Martins, Junior, Garcia, Luz, Maia, Melo, Cruz, Lima, Neto, Matos, Silva, Sousa, Souza, Nascimento, Alves, Braga, Gomes, Filho, Maciel, Santos, Soares, Amorim, Castro, César, Bastos, Costa, and Figueiredo