Last name יצחק (Isaac 
, Isak , יצחק 
, along with others...) , around the globe, is a widespread surname. The surname יצחק is habitual in Israel, where it is a widespread surname, Antigua and Barbuda, where it is a common surname, and Saint Kitts and Nevis (explore the name in all countries). Measured by absolute frequency, it most frequently occurs in Nigeria, Mexico, and Israel. Also, יצחק is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Isaac, Isaak, Isak | Kenya, Mexico, Ghana, Nigeria, United States |
| יצחק | Israel |
| Yitzchak | United Kingdom, Panama, South Africa, United States, Israel |
| Ismar | Mexico, Nigeria, United States, Brazil, Democratic Republic of the Congo |
| Исхак | Azerbaijan, Kazakhstan, Armenia, Russia, Kyrgyzstan |
| Yitzchok | South Africa, Spain, United States, Israel, Venezuela |
| Itzhak, Yitzhak | South Africa, Brazil, Mexico, United States, Israel |
| Icchak | Poland, United States, India, Brazil, Venezuela |
| Yitshak | Brazil, Mexico, Nigeria, United States, Israel |
| Yizhak | South Africa, United States, Canada, Israel, Venezuela |
| Itzchak | United Kingdom, South Africa, Mexico, United States, Israel |
| Ицхак | Lithuania, Russia, Belarus, Ukraine, Israel |
Ichak, Iiro, Iisakki, Ike, Is., Isaach, Isaack, Isaacs, Isaacus, Isac, Isacco, Isach, Isakas, Ishak, Isidoro, Issaak, Issac, Issak, Itschak, Itshak, Izaac, Izaak, Izak, Izhak, Izsak, Izsák, Izák, Jicchak, Jsac, Seckel, Ysaac, Айзек, Айк, Изаак, Ике, Исаак, Исаак, Айзек, Исаако, Исак, Исако, Ицхок, Ысқақ, Ісаак, Ісак, Іцхак, אייזיק, אייזקס, איציק, أوتو, إسحاق, إسحق, اسحاق, ايزاك, ইসহাক, アイク, イケ, and イサク
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יצחק יצחק Israeli poet and children's writer, IL (b. 1906) |
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| אברהם בן יצחק Israeli poet (1883-1950), IL (b. 1883) |
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רוברט בר יצחק IL (b. 1924) |
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אלישע בן יצחק painter, IL (b. 1943) |
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אמנון יצחק Haredi Orthodox Rabbi of Yemenite origin involved in Kiruv in Israel, IL (b. 1953) |
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יואב יצחק Israeli journalist, IL (b. 1957) |
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אברהם יצחק IL (b. 1973) |
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גיל יצחק Israeli footballer, IL (b. 1993) |
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| ישראל יצחק Israeli police officer, IL (b. 1953) |
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| יצחק בן יצחק IL (b. 1948) |
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| יואב יצחק Israeli singer, IL (b. 1958) |
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| ליאורה יצחק Israeli singer of Indian origin, IL (b. 1974) |
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| רן יצחק Israeli footballer, IL (b. 1987) |
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| עוזי בן יצחק IL |
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חן, יוסף, יעקב, יפרח, דיין, עזרא, וקנין, חיים, הרוש, אוחנה, אשכנזי, מזרחי, אליהו, אברהם, אמסלם, אטיאס, אזולאי, מימון, ביטון, יצחקי, סויסה, עובדיה, גבאי, אוחיון, ששון, בן דוד, טל, כץ, מור, משה, ממן, בכר, שמש, סבג, פרץ, לוי, דוד, דהן, עמר, חזן, חדד, כהן, אלבז, אדרי, מאיר, מלכה, ברוך, שלום, and פרידמן