Surname Issac (Issac 
, Айзек 
) , in the entire world, is a common cognomen. The last name Issac is characteristic of United Arab Emirates, where it is quite a common surname, Bahrain, where it is quite a rare surname, and Mauritius. Not in comparison with a country's population, the name is most common in India, Nigeria, and Egypt. Also, Issac is the forename as well as the last name.
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| Issac | Egypt, India, Nigeria, United States, Democratic Republic of the Congo |
| Айзек | Kazakhstan, Kyrgyzstan, Russia, Ukraine |
| george issac (b. 1944) |
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| james issac (b. 1960) |
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| lydia e issac researcher |
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| charles issac Sir Fellow 1692 - 1711 |
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| marianne samir makboul issac researcher |
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| hancy issac researcher |
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| mary issac politician in Saint Lucia |
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| neethu g issac researcher |
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| tom issac college basketball player (1968–1970) Texas-El Paso |
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| alwin issac researcher |
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| praveen kumar issac researcher |
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| biju issac researcher ORCID ID = 0000-0002-1109-8715 |
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| biju issac researcher (ORCID 0000-0002-7311-678X) |
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| morece issac college basketball player (2012–2012) Saint Francis (PA) |
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| rod issac player of American football, US (b. 1989) |
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