Surname Santillán (Santillán 
) , all over the world, is quite a rare family name. The surname Santillán is characteristic of Latin America and the Caribbean, particularly Ecuador, where it is a rare surname, Bolivia, and Argentina. In absolute terms, it most frequently occurs in Latin America and the Caribbean, particularly Mexico, Argentina, and Peru. Much less frequently, Santillán is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Santillán | Mexico, Peru, Argentina, Bolivia, Ecuador |
| josé anselmo ruiz de cortázar santillán ES (b. 1696) |
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ramón de santillán Spanish politician (1791-1863), ES (b. 1791) |
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gregorio santillán Argentinian politician (1832-1894), AR (b. 1832) |
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josé domingo santillán AR (b. 1870) |
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diego abad de santillán Spanish anarchist, author, economist (1897-1983), ES (b. 1897) |
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| rafael aguilar y santillán Mexican geographer, MX (b. 1863) |
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| maría teresa santillán Mexican singer, MX (b. 1893) |
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carlos santillán Argentine activist, AR (b. 1951) |
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| antonio santillán Spanish film director, ES (b. 1909) |
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maría laura santillán Argentine journalist, AR (b. 1962) |
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| diego santillán Spanish film director and screenwriter, ES (b. 1925) |
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mariano santillán Argentinian politician, AR |
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| atilio santillán Argentine trade unionist, AR (b. 1935) |
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| francisco polti santillán Catholic bishop, AR (b. 1938) |
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| rodolfo santillán Mexican rower, MX (b. 1947) |
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