Family name Saint-Sernin (Saint-Sernin 
) , across the world, is a rare last name. The family name Saint-Sernin is habitual in France, where it is a rare surname, and the United Kingdom, where it is an extremely rare surname. Parts of the name also exists independently as a first name Saint, and a last name Sernin.
| VARIANT | COUNTRY |
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| Saint-Sernin | France, United Kingdom |
| bertrand saint-sernin French philosopher, FR (b. 1931) |
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| frédéric de saint-sernin French politician, FR (b. 1958) |
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| jane saint-sernin |
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Luc, Cédric, Pauline, Gabriel, Géraud, Laurent, Thierry, Estelle, Etienne, Michelle, Aurélie, Caroline, Brigitte, Jérémy, Isabelle, Christian, Quitterie, Geneviève, Xavier, Madeleine-Sophie, Hubert, Geraud, Marc, Alix, Léa, Joel, Jean, Simon, Alain, Bruno, David, Manuel, Magali, Sabine, Arnaud, Agnès, Cedric, Pierre, Didier, Julien, and François-Xavier