Surname López-Portillo (López-Portillo 
) , globally, is an extremely rare family name. The surname López-Portillo is characteristic of Latin America and the Caribbean, particularly Mexico, where it is an extremely rare surname. Parts of the name also exists independently as a last name López, and a last name Portillo.
| VARIANT | COUNTRY |
|---|---|
| López-Portillo | Mexico |
| raúl pérez lópez-portillo (b. 1947) |
|