Surname Portillo (Portillo 
, פורטיו 
) , in the entire world, is a widespread family name. The cognomen Portillo is characteristic of Latin America and the Caribbean, particularly El Salvador, where it is a widespread surname, Honduras, where it is a common surname, and Paraguay (explore the name in all countries). Not in comparison with a country's population, it is the most numerous in Latin America and the Caribbean, particularly Mexico, El Salvador, and Honduras. Very seldom, Portillo is the forename as well as the last name.
| francisco de lópez portillo MX (b. 1713) |
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| josé eugenio del portillo Argentinian lawyer, AR (b. 1760) |
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| isabel maría schiaffino portillo ES (b. 1750) |
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| rafael osorio y portillo ES (b. 1780) |
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pedro portillo Peruvian politician (1856-1916), PE (b. 1856) |
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| josé filiberto portillo Spanish military personnel, ES (b. 1810) |
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manuel bravo portillo Spanish police officer, ES (b. 1876) |
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| leonardo lópez portillo MX (b. 1820) |
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| sebastián aguado y portillo Spanish sculptor (1854-1933), ES (b. 1854) |
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gregorio a. portillo AR (b. 1897) |
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| bruno portillo y portillo ES (b. 1855) |
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iris portillo Argentinian actor, AR (b. 1918) |
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| ramón gómez portillo Colombian journalist, CO (b. 1874) |
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| enrique del portillo (b. 1871) |
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lourdes portillo American filmmaker, MX (b. 1944) |
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