Cognomen Kleine-Niesse (Kleine-Niesse 
) , around the globe, is a very rare family name. The surname Kleine-Niesse is habitual in Western Europe, particularly Germany, where it is a very rare surname. Parts of the name also exists independently as a last name Kleine, and a last name Niesse.
| VARIANT | COUNTRY |
|---|---|
| Kleine-Niesse | Germany |