Last name Karpuzov (Karpuzov 
) , in the entire world, is a rare family name. The surname Karpuzov is habitual in Bulgaria, where it is quite a rare surname, Serbia, where it is a rare surname, and Estonia. Measured by absolute frequency, it is commonest in Bulgaria, Serbia, and Russia.
| VARIANT | COUNTRY |
|---|---|
| Karpuzov | Russia, Estonia, Serbia, Bulgaria, Canada |