Last name Gupton (Gupton 
) , globally, is quite a rare cognomen. The family name Gupton is habitual in the United States, where it is a rare surname, Canada, where it is a very rare surname, and Germany, where it is an extremely rare surname.
| VARIANT | COUNTRY |
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| Gupton | Germany, Canada, France, United Kingdom, United States |
| william gupton American politician, US (b. 1870) |
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| damon gupton American actor and orchestral conductor (born 1973), US (b. 1973) |
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| john gupton college basketball player (1965–1967) Virginia Military Institute |
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| john t. gupton Professor of Chemistry, University of Central Florida |
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| stephanie l gupton researcher |
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| james ronald gupton Ph.D. Vanderbilt University 1976 |
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| kyle gupton American professional basketball player, US (b. 1990) |
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