Family name Zafrilla (Zafrilla 
) , across the world, is a rare surname. The family name Zafrilla is characteristic of Spain, where it is a rare surname, France, and Argentina, where it is a very rare surname. Not in comparison with a country's population, it is the most numerous in Spain, France, and Mexico. Also, Zafrilla is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Zafrilla | Spain, Mexico, United States, Argentina, France |
| marcos de moriana y zafrilla Roman Catholic bishop (b. 1745) |
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| sofia gomez zafrilla Spanish politician, ES |
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| pilar zafrilla researcher (ORCID 0000-0002-1463-7120) |
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| jorge enrique zafrilla researcher |
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| basilio zafrilla researcher |
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