Last name Uesugi (ウエスギ 
, Uesugi 
) , in all the world, is a rare surname. The family name Uesugi is habitual in North Macedonia, where it is a rare surname, Latvia, and Slovakia. Not in comparison with a country's population, it most frequently occurs in Japan, the United States, and Brazil. More frequently, Uesugi is the forename as well as the last name.
| uesugi norifusa samurai of the Nanbokucho period (b. 1250) |
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| uesugi kiyoko (b. 1270) |
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| uesugi noriaki daimyo of the Nanbokucho period (b. 1306) |
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| uesugi norimasa daimyo of the early-Muromachi period (b. 1335) |
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| uesugi mochisada (b. 1402) |
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| uesugi mochitomo daimyo of the mid-Muromachi period (b. 1416) |
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| uesugi fusatomo (b. 1421) |
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| uesugi kagenobu Japanese samurai and general (b. 1550) |
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| uesugi ujinori (b. 1550) |
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| uesugi norihiro (b. 1550) |
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uesugi tsunakatsu daimyō of Yonezawa Domain in Dewa Province during the Edo period Tokugawa Shogunate, Japan (b. 1639) |
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| uesugi tsunanori (b. 1663) |
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| uesugi yoshinori (b. 1684) |
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| uesugi yoshinaga Hatamoto of the mid-Edo period (b. 1773) |
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| uesugi kazutsura (b. 1775) |
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