Family name Spiridon (Spiridon 
, Спиридон 
, Σπυρίδων ) , around the globe, is quite a common cognomen. The last name Spiridon is habitual in Romania, where it is quite a common surname, Georgia, where it is quite a rare surname, and Bulgaria. Also, Spiridon is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Spiridon | Georgia, Romania, Greece, Bulgaria, Italy |
| Спиридон | Ukraine, Kazakhstan, Armenia, Russia, Bulgaria |
| Σπυρίδων | Greece |
| spiridon vlantis Greek scholar, IT (b. 1765) |
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| spiridon zhevakhov Russian general, DE (b. 1768) |
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spiridon osipovich esadze (b. 1813) |
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| spiridon jurjewitsch destunis (b. 1782) |
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| spiridon jović (1801-1836), Serbian writer and ethnographer, AT (b. 1801) |
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| spiridon dscherow MK (b. 1800) |
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| spiridon m. michajlov (1821-1861) (b. 1821) |
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spiridon velev MK (b. 1863) |
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| spiridon zambelios GR (b. 1815) |
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spiridon ilo Albanian politician (1876-1950), AL (b. 1876) |
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spiridon mirchev MK (b. 1866) |
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| ignace spiridon IT (b. 1848) |
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| spiridon popescu Romanian prose writer (1864-1933), RO (b. 1864) |
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| spiridon boiță Romanian lawyer, RO (b. 1869) |
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spiridon mattar Catholic bishop, LB (b. 1921) |
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