Cognomen Sophronius (Софроний 
, Sophronius 
) , throughout the world, is a rare family name. The surname Sophronius is characteristic of Bulgaria, where it is a rare surname, Russia, where it is a very rare surname, and Kazakhstan. Also, Sophronius is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Софроний | Bulgaria, Ukraine, Kazakhstan, Russia |
| Sophronius | Israel |
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sophronius eusebius hieronymus Catholic and Eastern Orthodox saint and Doctor of the Church, SI (b. 345) |
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| sophronius ii of jerusalem patriarch of Jerusalem (b. 1050) |
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| sophronius iv of jerusalem Orthodox patriarchate (b. 1505) |
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| sophronius of aenos GR (b. 1789) |
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| sophronius s. landt American politician, US (b. 1842) |
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sophronius of tarnovo TR (b. 1888) |
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| sophronius ιιι of anchialus |
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