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Cognomen Sixto (Sixto , סיקסטו , Сиксто) , worldwide, is a common family name. The cognomen Sixto is characteristic of Latin America and the Caribbean, particularly Nicaragua, where it is quite a common surname, Mexico, and Honduras (explore the name in all countries). Measured by absolute frequency, the name is most common in Mexico, Spain, and Venezuela. Likewise, Sixto is the forename as well as the last name.