Surname Serena De La Cruz (Serena De La Cruz 
) , all around the world, is an extremely rare last name. The surname Serena De La Cruz is habitual in Latin America and the Caribbean, particularly Chile, where it is an extremely rare surname. More frequently, Serena De La Cruz is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Serena De La Cruz | Ecuador, Chile |