Cognomen Sephikwe (Sephikwe 
) , globally, is a very rare last name. The last name Sephikwe is characteristic of Sub-Saharan Africa, particularly Botswana, where it is quite a rare surname, and South Africa, where it is an extremely rare surname. Very seldom, Sephikwe is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Sephikwe | Botswana, South Africa |