Cognomen Santiago-Rios (Santiago-Rios 
) , across the world, is an extremely rare surname. The last name Santiago-Rios is habitual in Northern America, particularly the United States, where it is an extremely rare surname. Parts of the name also exists independently as a last name Santiago, and a last name Rios.
| VARIANT | COUNTRY |
|---|---|
| Santiago-Rios | United States |