Last name Santiago Demetrio (Santiago Demetrio 
) , throughout the world, is an extremely rare family name. The cognomen Santiago Demetrio is habitual in Latin America and the Caribbean, particularly Chile, where it is an extremely rare surname. Much more frequently, Santiago Demetrio is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Santiago Demetrio | Ecuador, Chile, Peru |