Last name Santana Palacios (Santana Palacios 
) , in the entire world, is a very rare surname. The cognomen Santana Palacios is habitual in Latin America and the Caribbean, particularly Ecuador, where it is a rare surname, and Chile, where it is a very rare surname.
| VARIANT | COUNTRY |
|---|---|
| Santana Palacios | Chile, Ecuador |