Cognomen Santángelo (Santángelo 
) , worldwide, is a very rare surname. The surname Santángelo is characteristic of Latin America and the Caribbean, particularly Uruguay, where it is a rare surname, Argentina, where it is a very rare surname, and Venezuela, where it is an extremely rare surname. Much less frequently, Santángelo is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Santángelo | Venezuela, Argentina, Uruguay |
| salvador santángelo Argentinian actor, AR (b. 1916) |
|
|
| jorge cocco santángelo (b. 1936) |
|
|
| mariana santángelo Argentinian actress, AR (b. 1975) |
|